GP-write Announces ‘Ultra-safe Cells’ as Featured Community Project

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GP-write Announces ‘Ultra-safe Cells’ as Featured Community Project


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ANNOUNCING … GP-Write’s Genome Design Software Challenge
A cash prize for the best software!
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Recent Leadership Changes at GP-write • View Announcement

苹果机ins要爬墙吗

苹果机ins要爬墙吗


The Genome Project-write (GP-write) is an open, international research project led by a multi-disciplinary group of scientific leaders who will oversee a reduction in the costs of engineering and testing large genomes in cell lines more than 1,000-fold within ten years.

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The overarching goal of such an effort is to understand the blueprint for life provided by the Human Genome Project (HGP-read).

HGP-read aimed to “read” a human genome. Successfully completed in 2003, HGP-read is now widely recognized as one of the great feats of exploration, one that sparked a global revolution in science and medicine, particularly in genomic-based diagnostics and therapeutics.

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GP-write press release may 2018Download Press Release: Ultra-safe Cells Resistant to Natural Viruses Announced as First GP-write Grand-scale Project
GP-write Statement of Principle on Human Germline Modification
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Writing DNA is the future of science and medicine, and holds the promise of pulling us forward into a better future. While reading DNA code has continued to advance, our capability to write DNA code remains limited, which in turn restricts our ability to understand and manipulate biological systems. GP-write will enable scientists to move beyond observation to action, and facilitate the use of biological engineering to address many of the global problems facing humanity.

Synthesis of
Large Genomes:

苹果机ins要爬墙吗


苹果机ins要爬墙吗


On October 31st, 2015, leaders in the fields of genetics and synthetic biology convened at the Institute for Systems Genetics at NYU Langone Medical Center in New York City to conceptualize and discuss the feasibility of a bold quest: synthesizing a human genome (HGP-write).

As defined at this initial meeting, HGP-write is an open, international scientific research project led by a group of scientific leaders from multiple disciplines, including biology, chemistry, computational biology, engineering, social science, and ethics. The primary goal of the project is to reduce the costs of engineering, or writing, human and other large genomes in cell lines more than 1,000-fold within ten years, in order to understand the blueprint for life provided by the Human Genome Project (HGP-read).

On May 10, 2016, more than 130 scientists, industry leaders, ethicists and policy makers steeped in human biology, health and synthetic biology came together in Boston for an expanded organizing meeting of HGP-write. This meeting focused on the design and technical issues, ethical and social issues, and industry involvement of HGP-write. Based on discussions at this meeting, the GP-write Leadership Group decided to broaden the scope of the project to include all large animal and plant genomes, including the human genome, and make HGP-write one component of GP-write.

The second GP-write annual meeting was held on May 9th and 10th, 2017, at the New York Genome Center in New York City. This meeting explored the concrete steps that GP-write can take to solve some of the most important problems facing humanity, including how to move from a carbon-based economy towards a biological one that is sustainable? How to further advance cures for disease? How to responsibly communicate the risks and benefits of this project to the world? The Agenda also included the introduction of new pilot project proposals, as well as the commencement of GP-write working groups to discuss project roadmaps, including scientific direction, technology development, ethical, social and legal engagement, standards and infrastructure development, amongst others.

There were more than 250 attendees from 10 countries at this oversubscribed meeting. The meeting participants were academic and industry scientists, ethicists, lawyers, educators, citizen scientists, artists, policymakers, technologists and lay people. This meeting also attracted a great deal of interest from the press, many of whom were on-site throughout the meeting to attend a press briefing as well as a tour of the genome foundry at the Institute for Systems Genetics at NYU Langone Health.

The October and May meetings are part of a series of scientific discussions amongst the community that have been unfolding over the past several years. Initially, these meetings were focused on the synthesis and testing of yeast and bacterial genomes, and the future of synthetic biology. More recently, the focus has shifted to synthesis of variations within large genomes as a pathway to addressing some of the many global challenges facing humanity, including healthcare and the environment.

Funding is expected to come from public, private, philanthropic, industry and academic sources globally. Autodesk has contributed a leadership gift of $250,000 to seed the planning and launch of GP-write. As of May 2017, approximately $200 million in GP-write related funding has been made available across multiple institutions.

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GP-write is being conducted in phases with milestones, metrics, and assessments. Initial proposed pilot projects will first be completed to evaluate feasibility and value, similar to other large-scale endeavors such as HGP-read and the Synthetic Yeast Project (Sc2.0). Furthermore, these projects will be chosen to provide early stage resources valuable for biomedical research and/or biotechnology production.


HGP-write-launch
Download the May 2018 Meeting Summary